Edoxaban tsis zoo ib yam li Clopidogrel. Nov yog qhov sib txawv tseem ceeb ntawm ob:
1, chav kawm tshuaj thiab cov txheej txheem ntawm kev ua
Edoxaban:
Chav Kawm: tshiab qhov ncauj ncaj qha thrombin inhibitor.
Mechanism ntawm kev txiav txim: tiv thaiv cov txheej txheem coagulation los ntawm inhibiting cov haujlwm ntawm thrombin, yog li ua tiav cov nyhuv anticoagulant.
Kev Siv Tseem Ceeb: Rau kev tiv thaiv kev pheej hmoo mob stroke thiab venous thromboembolism hauv cov neeg mob uas tsis yog -valvular atrial fibrillation, nrog rau kev kho mob ntawm cov hlab ntsha sib sib zog nqus (DVT) thiab pulmonary embolism (PE).
Clopidogrel:
Qib: platelet aggregation inhibitor.
Mechanism ntawm kev ua: Los ntawm thaiv ADP (adenosine diphosphate) receptors, nws txo platelet activation thiab aggregation, yog li tiv thaiv thrombosis.
Kev siv tseem ceeb: Rau kev tiv thaiv kab mob plawv, mob stroke thiab lwm yam kab mob thrombotic, tshwj xeeb tshaj yog cov xwm txheej atherosclerotic thrombotic xws li ischemic stroke thiab myocardial infarction.
2. Ceev faj rau kev siv
Edoxaban:
Kev pheej hmoo los ntshav: Raws li cov tshuaj tiv thaiv coagulant, thawj qhov kev pheej hmoo ntawm Edoxaban yog los ntshav, suav nrog lub neej - hem los ntshav. Yuav tsum tau saib xyuas cov neeg mob los ntshav thaum lub sijhawm siv.
CONTRAINDICATIONS THIAB DRUG INTERACTIONS: Tshwj xeeb contraindications thiab kev cuam tshuam nrog lwm yam tshuaj muaj nyob thiab yuav tsum tau nyeem cov lus qhia ntxaws ntxaws thiab siv nyob rau hauv kev saib xyuas kev kho mob.
Clopidogre:
Kev pheej hmoo los ntshav: Txawm hais tias Clopidogrel ua feem ntau ntawm cov platelets, kev noj ntau dhau kuj tuaj yeem ua rau los ntshav ntev.
Tshuaj rau cov neeg tshwj xeeb: Clopidogrel yog contraindicated rau cov poj niam cev xeeb tub thiab pub niam mis, cov neeg uas tsis haum rau cov khoom, cov neeg uas raug kev txom nyem los ntawm ulcers thiab intracranial haemorrhage. Cov neeg mob uas xav tau kev phais yuav tsum tsis txhob siv rau qee lub sijhawm ua ntej kev phais kom tsis txhob muaj kev pheej hmoo los ntshav.
3. Cov ntaub ntawv ntxiv
Edoxaban:
TSEEM CEEB: Thaum Lub Ib Hlis 8, 2015, US Food and Drug Administration (FDA) tau pom zoo Daiichi Sankyo Co.'s anticoagulant tshuaj Savaysa (edoxaban).
KEV KHO MOB: Nws ua tau zoo thiab kev nyab xeeb hauv kev tiv thaiv kev mob stroke thiab venous thromboembolism hauv cov neeg mob atrial fibrillation tau txheeb xyuas hauv qhov loj - kev sim tshuaj loj.
Clopidogrel:
WIDELY SIV: Vim nws txoj kev ua tau zoo thiab kev nyab xeeb profile, Clopidogrel tau siv dav hauv kev kho mob.
Kev Kho Kom Zoo: Kev siv tshuaj ntau npaum li qhov sib txawv ntawm tus kheej thiab yuav tsum tau noj rau lub sijhawm ntev raws li kev saib xyuas ntawm tus kws kho mob thiab kev saib xyuas tsis tu ncua ntawm kev pheej hmoo los ntshav.
Hauv cov ntsiab lus, Edoxaban thiab Clopidogrel muaj qhov sib txawv tseem ceeb ntawm cov tshuaj hauv chav kawm, kev ua haujlwm, kev siv tseem ceeb thiab kev ceev faj rau kev siv. Yog li ntawd, kev xaiv thiab siv ob yam tshuaj no yuav tsum ua raws li tus neeg mob tus mob thiab tus kws kho mob cov lus qhia.
Yog tias koj xav paub ntxiv, thov nyem rau ntawm daim duab saum toj no!