Kev ua xua thiab tshuaj tua kab mob ntawm 4-Hydroxyisophthalic Acid
CAS 636-46-4 4-HYDROXYISOPHTHALIO Acid yog cov khoom lag luam los ntawm kev tsim cov salicylic acid los ntawm Kolbe-Schmitt cov tshuaj tiv thaiv thiab tau pom tias yog cov khoom tseem ceeb
4-Hydroxyisophthalic acid yog cov khoom lag luam los ntawm Kolbe-Schmitt cov tshuaj tiv thaiv siv hauv salicylic acid ntau lawm thiab yog ib qho tseem ceeb ntawm cov 'xim av plua plav' residues los ntawm cov txheej txheem sublimation siv los ntxuav salicylic acid. Ib qho piv txwv ntawm cov residue no tau pom tias muaj 82% ntawm 4-hydroxyisophthalic acid, 10% salicylic acid, thiab 3% 2-hydroxyisophthalic acid, nrog rau qee yam khoom siv tsis zoo.
Qhov kev sib txuas no lub peev xwm rau kev muaj peev xwm loj tau coj mus rau nws qhov kev tshawb nrhiav ua ib feem ntawm kev tshawb fawb. Muab nws cov qauv zoo sib xws rau salicylic acid, cov kws tshawb fawb tau pom tias 4-hydroxyisophthalic acid tuaj yeem faib cov khoom siv tshuaj zoo sib xws. Kev ntsuam xyuas tshuaj thaum ntxov tau qhia tias 4-hydroxyisophthalic acid muaj cov tshuaj tua kab mob, nrog rau nws cov koob tshuaj nruab nrab (ED50) yog 303 mg / kg hauv nas. Qhov no yog kwv yees li 4.1% ntawm cov dej num ntawm codeine, thiab nws muaj li 10% ntawm codeine toxicity. Hauv qhov sib piv, cov tshuaj aspirin tau pom tias muaj tshuaj lom ntau dua thiab tsis muaj txiaj ntsig zoo hauv kev sib piv. Tsis tas li ntawd, 4-hydroxyisophthalic acid tau pom zoo cov tshuaj tua kab mob zoo sib xws rau cov tshuaj aspirin hauv cov luav, txo qhov kub taub hau los ntawm pyrogen los ntawmProteus vulgaris.
Peb Yog Leej Twg
GneehemNrog ntau xyoo dhau los ntawm kev tshawb fawb, kev tsim khoom thiab kev lag luam organic chemicals, Gnee chemicals Ltd. yog tam sim no lub ntiaj teb kev lag luam ntawm kev tshawb fawb, kev tsim kho thiab kev tsim tshuaj.