Blonanserin: Khoom thiab siv
I. Kev Taw Qhia
Blonanserin tau tsim los ua cov tshuaj tiv thaiv kab mob hauv Nyij Pooj thiab tau pom zoo rau kev kho tus mob schizophrenia. Nws yog ib tug series ntawm 4-phenyl-2-(1-piperazinyl) pyridines.
II. Mechanism ntawm Action
Blonanserin ua tus antagonist ntawm dopamine D2, D3, thiab serotonin 5-HT2A receptors. Nws khi rau thiab inhibits cov receptors nrog siab affinity. Nws muaj affinity tsawg rau lwm yam dopamine thiab serotonin receptors nrog rau muscarinic, adrenergic, thiab histamine receptors. Cov tshuaj no tswj cov neurotransmitters (piv txwv li, dopamine, serotonin) hauv lub hlwb kom txhim kho cov tsos mob xws li kev ntxhov siab, ntxhov siab, thiab txo qis kev mob siab.
III. Yam ntxwv
Blonanserin yog dopamine-serotonin antagonist nrog kev sib raug zoo rau D2,3 thiab 5HT2A receptors. Nws affinity rau muscarinic, histaminic, thiab adrenergic receptors yog tsawg heev, ua rau kom txo tau qhov hnyav nce, txawv txav lipid los yog qabzib metabolism, thiab mob plawv.
IV. Siv nyob rau hauv kev kho mob ntawm kev puas hlwb
Schizophrenia: Nws yog tsuas yog siv los kho tus mob schizophrenia los tswj cov tsos mob xws li kev hnov lus, kev xav tsis zoo, kev xav tsis zoo, thiab kev tshem tawm hauv zej zog.
Lwm yam kev puas siab puas ntsws: kuj tseem siv tau rau hauv kev kho mob ntawm lwm yam kev puas siab puas ntsws uas muaj kev cuam tshuam hauv kev xav, kev xav, thiab kev coj cwj pwm.
V. Tswj cov tsos mob
Pab txo qis cov tsos mob zoo xws li kev hnov lus thiab kev xav tsis zoo nrog rau cov tsos mob tsis zoo xws li apathy, kev tawm tsam, thiab tsis muaj kev txhawb siab. tuaj yeem txhim kho kev txawj ntse thiab kev ua haujlwm tag nrho hauv cov neeg mob uas muaj kev puas siab puas ntsws.
Yog tias koj xav paub ntxiv, thov nyem rau ntawm daim duab saum toj no!