Kev tshuaj xyuas txog kev nce qib tsis ntev los no ntawm cyanidin-3-glucoside: biotransformation, nqus, bioactivity thiab kev siv ntawm nano-encapsulation.
Anthocyanins yog ib chav kawm ntawm kev noj haus polyphenols uas nthuav tawm cov cuab yeej thev naus laus zis thiab bioactive-muaj feem cuam tshuam. C3G yog absorbed nyob rau hauv nws cov unmodified molecular daim ntawv nyob rau hauv lub Upper digestive ib ntsuj av, mus los ntawm lub ncua thawj-kauj metabolism hauv thiab nws cov metabolites nkag mus rau hauv cov hlab ntsha. C3G metabolites muaj cov txiaj ntsig kev noj qab haus huv xws li antioxidant, cardio-tiv thaiv, tiv thaiv kab mob, neuroprotective, tiv thaiv mob qog noj ntshav, tiv thaiv ntshav qab zib, thiab kev ua haujlwm tiv thaiv thrombotic. Txawm li cas los xij, kev ua tau zoo thiab kev faib tawm ntawm C3G hauv tib neeg lub cev raug txwv vim nws tsis tshua muaj kev ruaj ntseg thiab bioaccessibility. Kev tshoov siab, cov lipid-, polysaccharide-, protein-, thiab nanocapsule-txuas nrog conjugates tau ua tiav lub hom phiaj xa khoom nrog txhim kho bioaccessibility thiab tswj kev tso tawm. Hauv qhov kev tshuaj xyuas no, cov qauv kev nqus thiab kev thauj mus los, cov txheej txheem decomposition thiab cov metabolism, kev ua haujlwm ntawm cov txheej txheem, thiab cov txheej txheem txhim kho rau kev txhim kho bioavailability ntawm C3G tau sau tseg. Ntxiv mus, cov yam ntxwv ntawm lub plab microbiota txoj cai, C3G-mediated cytoprotection thiab cov ntaub ntawv sib txawv biocompatible tau tham luv luv.
Cyanidin 3-glucoside (C3G) yog ib qho kev sib xyaw uas muaj nyob hauv cov khoom noj uas muaj cov khoom noj muaj zog antioxidant. Nws paub txog nws lub peev xwm los tshem tawm cov dawb radicals, txo oxidative kev nyuaj siab, thiab muaj peev xwm muab cov txiaj ntsig kev noj qab haus huv xws li tshuaj tiv thaiv kab mob ntshav qab zib thiab tshuaj tiv thaiv kab mob.
Cyanidin -3-glucoside (C3G) (Fig. 4K) yog ib hom anthocyanin feem ntau pom nyob rau hauv dub mov (Oryza sativa). C3G muab cov txiaj ntsig zoo rau kev kho mob ntshav qab zib mellitus, suav nrog cov kab mob cataracts thiab lwm yam oxidative kev nyuaj siab vim kev puas tsuaj (Lee li al., 2014). Mechanistically, C3G inhibits NF-κB activation thiab cyclooxygenase-2 (COX-2) qhia, txo apoptosis ntawm lub lens epithelial hlwb, thiab thaum kawg alleviates clouding ntawm cov ntshav qab zib cataract lens (Song et al., 2020). Txog niaj hnub no, nws paub tias C3G yog flavonol uas tiv thaiv kab mob ntshav qab zib cataracts feem ntau ntawm inhibiting lub lens cell apoptosis.
Anthocyanin feem ntau pom muaj nyob rau hauv cov noob qoob loo ntawm cov xim dub xws li taum dub, taum ntau, cowpea, txiv laum huab xeeb, thiab lentils. Ntawm lwm cov anthocyanin, cyanidin 3 glucoside yog qhov loj anthocyanin pom hauv legumes. Ib sab ntawm cov tshuaj antioxidant siab, anthocyanin los ntawm legumes tau tshaj tawm tias muaj kev tiv thaiv kev mob ntshav siab, tiv thaiv kab mob, tshuaj tua kab mob, tshuaj tua kab mob, thiab kev ua haujlwm antimutagenic. Nws kuj tseem txhim khu kev nco, txhim kho kev paub, thiab inhibits LDL oxidation. Ua kom noj cov legumes rau tib neeg noj txhua hnub yuav tsum tau pom zoo vim lawv cov khoom muaj txiaj ntsig zoo rau kev noj qab haus huv. Tsis tas li ntawd, kev tshawb fawb ntxiv ntawm daim ntawv thov lossis kev koom ua ke ntawm legumes hauv khoom noj txom ncauj lossis lwm yam khoom noj khoom haus hauv kev lag luam yuav tsum tau ua kom zoo dua txhawm rau txhawm rau txhawm rau kom tau txais cov anthocyanin thiab lwm yam bioactive compound hauv legumes.