Kev tshuaj xyuas txog kev nce qib tsis ntev los no ntawm cyanidin-3-glucoside: biotransformation, nqus, bioactivity thiab kev siv ntawm nano-encapsulation.
Anthocyanins yog ib chav kawm ntawm kev noj haus polyphenols uas nthuav tawm thev naus laus zis thiab bioactive - cov khoom muaj feem xyuam. C3G yog absorbed nyob rau hauv nws unmodified molecular daim ntawv nyob rau hauv lub Upper digestive ib ntsuj av, mus los ntawm lub ncua ua ntej -kab metabolism thiab nws cov metabolites nkag mus rau hauv cov hlab ntsha. Cov C3G metabolites muaj cov txiaj ntsig kev noj qab haus huv xws li antioxidant, cardio- tiv thaiv, tiv thaiv - mob, neuroprotective, tiv thaiv- mob qog noj ntshav, tiv thaiv- mob ntshav qab zib, thiab tiv thaiv- cov haujlwm thrombotic. Txawm li cas los xij, kev ua tau zoo thiab kev faib tawm ntawm C3G hauv tib neeg lub cev raug txwv vim nws tsis tshua muaj kev ruaj ntseg thiab bioaccessibility. Kev tshoov siab, lipid-, polysaccharide-, protein-, thiab nanocapsule- koom nrog kev sib txuas tau ua tiav lub hom phiaj xa khoom nrog kev txhim kho bioaccessibility thiab tswj kev tso tawm. Hauv qhov kev tshuaj xyuas no, cov qauv kev nqus thiab kev thauj mus los, cov txheej txheem decomposition thiab cov metabolism, kev ua haujlwm ntawm cov txheej txheem, thiab cov txheej txheem txhim kho rau kev txhim kho bioavailability ntawm C3G tau sau tseg. Tsis tas li ntawd, cov kev cai ntawm lub plab microbiota txoj cai, C3G-kev kho cytoprotection thiab cov ntaub ntawv sib txawv ntawm cov khoom siv biocompatible tau tham luv luv.
Cyanidin 3-glucoside (C3G) yog ib hom tshuaj muaj nyob hauv cov nroj tsuag- cov khoom noj uas muaj zog antioxidant zog. Nws paub txog nws lub peev xwm los tshem tawm cov dawb radicals, txo cov kev ntxhov siab oxidative, thiab muaj peev xwm muab cov txiaj ntsig kev noj qab haus huv xws li tshuaj tiv thaiv - mob ntshav qab zib thiab tshuaj tiv thaiv kab mob.
Cyanidin-3-glucoside (C3G) (Fig. 4K) yog ib hom anthocyanin feem ntau pom muaj nyob rau hauv dub nplej (Oryza sativa). C3G muab cov txiaj ntsig zoo rau kev kho mob ntshav qab zib mellitus, suav nrog cov kab mob cataracts thiab lwm yam oxidative kev nyuaj siab vim kev puas tsuaj (Lee li al., 2014). Mechanistically, C3G inhibits NF-κB activation thiab cyclooxygenase-2 (COX-2) qhia, txo apoptosis ntawm lub lens epithelial hlwb, thiab thaum kawg alleviates clouding ntawm cov ntshav qab zib cataract lens (Song li al., 2020). Txog niaj hnub no, nws paub tias C3G yog flavonol uas tiv thaiv kab mob ntshav qab zib cataracts feem ntau ntawm inhibiting lub lens cell apoptosis.
Anthocyanin feem ntau pom muaj nyob rau hauv cov noob qoob loo ntawm cov xim dub xws li taum dub, taum ntau, cowpea, txiv laum huab xeeb, thiab lentils. Ntawm lwm cov anthocyanin, cyanidin 3 glucoside yog qhov loj anthocyanin pom hauv legumes. Ib sab ntawm kev ua haujlwm antioxidant siab, anthocyanin los ntawm legumes tau tshaj tawm tias muaj tshuaj tiv thaiv - mob ntshav siab, tiv thaiv - mob, tshuaj tua kab mob, tshuaj tiv thaiv kab mob, thiab kev ua haujlwm antimutagenic. Nws kuj tseem txhim khu kev nco, txhim kho kev paub, thiab inhibits LDL oxidation. Ua kom noj cov legumes rau tib neeg noj zaub mov txhua hnub yuav tsum tau pom zoo vim lawv cov khoom muaj txiaj ntsig zoo rau kev noj qab haus huv. Tsis tas li ntawd, kev tshawb fawb ntxiv ntawm daim ntawv thov lossis kev koom ua ke ntawm legumes hauv khoom noj txom ncauj lossis lwm yam khoom noj khoom haus hauv kev lag luam yuav tsum tau ua kom zoo dua txhawm rau txhawm rau txhawm rau kom tau txais cov anthocyanin thiab lwm yam bioactive compound hauv legumes.