I. Indications rau Amphotericin B
Amphotericin B feem ntau yog qhia rau kev kho cov kab mob loj hlob zuj zus thiab muaj peev xwm ua rau muaj kab mob fungal.
Cov kab mob fungal: Nws yog ib qho tshuaj tseem ceeb rau kev kho cov kab mob fungal uas ua rau muaj kev phom sij los ntawm ntau yam fungi xws li invasive candidiasis, cryptococcosis, aspergillosis, thiab mucormycosis. Cov kab mob no tuaj yeem tshwm sim hauv cov neeg mob immunocompromised zoo li cov neeg muaj HIV / AIDS, cov kws khomob khomob lossis hloov pauv hauv nruab nrog cev, lossis cov neeg muaj kabmob hnyav.
Cov kab mob fungal sib sib zog nqus: Yuav siv tau rau cov kab mob fungal tob tob uas cuam tshuam rau lub cev xws li lub ntsws, lub raum, lub siab, thiab lub hlwb.
Nws yog cov tshuaj tiv thaiv kab mob uas tau pom zoo los ntawm US Food and Drug Administration (FDA) rau kev kho mob ntawm ntau hom kab mob fungal, suav nrog histoplasmosis thiab cryptococcosis.
Nws muaj qhov dav dav ntawm cov tshuaj tiv thaiv kab mob thiab muaj txiaj ntsig zoo rau ntau yam kab mob fungal xws li Candida hom, Histoplasma capsulatum, Cryptococcus neoformans, Blastomyces dermatitidis, thiab Coccidioides immitis.
Cov hauv qab no yog cov chaw siv ntawm cov khoom:
II. Empirical Therapy
Qee qhov xwm txheej uas muaj kev xav tias muaj kab mob fungal loj tab sis cov kab mob tshwj xeeb tseem tsis tau txheeb xyuas, amphotericin B yuav raug siv los ua kev kho mob empirical. Qhov no yog qhov tseem ceeb tshwj xeeb tshaj yog rau cov neeg mob hnyav uas qhov kev ncua sij hawm kho mob tuaj yeem ua rau muaj kev phom sij rau lub neej.
Cov hauv qab no yog cov chaw siv ntawm cov khoom:
III. Cov kab mob Refractory
Rau cov kab mob fungal uas tiv taus lwm yam tshuaj tiv thaiv kab mob lossis nyuaj kho, amphotericin B yuav raug txiav txim siab. Nws feem ntau yog siv los ua qhov chaw kawg thaum lwm txoj kev kho mob ua tsis tiav.
IV. Ceeb toom
Nws yuav tsum tau muab sau tseg tias amphotericin B muaj kev phiv loj heev, thiab nws siv yuav tsum tau ceev faj saib xyuas thiab tswj. Amphotericin B yuav tsum tsis txhob siv rau cov neeg mob uas ib txwm suav neutrophil los kho cov kab mob uas tsis muaj kab mob xws li qhov chaw mos candidiasis, qhov ncauj thrush, thiab esophageal candidiasis.
Yog tias koj xav paub ntxiv, thov nyem rau ntawm daim duab saum toj no!