CAS 2353-33-5|5- {-2 '- deoxy cytidine

Cov khoom lag luam

{{0 {0}}} -2}}} '}' - deoxy cytidine yog ib qho tseem ceeb organic. Nws cov mis molecular yog c₈h₁₂n₄o₄, nws lub zog molecular yog 228.2, thiab nws tus CAS daim ntawv sau npe tus lej yog}}}. Nws tseem muaj aliases nrog rau decitabine.

5-Aza-2'-deoxy Cytidine feem ntau tshwm raws li cov hmoov dawb crystalline. Nws melting point yog hais txog 200 degree, thiab nws decomposes ntawm qhov kub thiab txias. Nws qhov kub kub yog 485.8 degree (ntawm qhov siab ntawm 760 mmHg). Nws yog qhov ruaj khov nyob rau hauv ib txwm muaj, tab sis nws yuav nkag siab rau lub teeb lossis huab cua, thiab tsis muaj zog oxidants.

Cov ntaub ntawv yooj yim

Cov ntaub ntawv kev nyab xeeb

Lom zem
Nws muaj qee yam toxicity thiab tuaj yeem ua rau lub cev puas tsuaj xws li cov pob txha, daim siab, thiab ob lub raum. Cov kev phiv tshwm sim feem ntau muaj xws li cov pob txha pob txha, neutropenia, thrombocytopenia, anemia, xeev siab, ntuav, raws plab, ua npaws, thiab lwm yam.

Kev siv ceev faj
Nws yuav tsum tau siv nyob rau hauv kev taw qhia ntawm ib tug kws kho mob, nruj me ntsis raws li tus kws kho mob cov lus qhia, thiab ua tib zoo saib xyuas cov ntshav niaj hnub, lub siab thiab lub raum kev ua haujlwm thiab lwm yam kev ntsuas txhawm rau txheeb xyuas thiab cuam tshuam cov kev cuam tshuam tsis zoo raws sijhawm. Nyob rau tib lub sijhawm, kev saib xyuas yuav tsum tau them nyiaj rau kev khaws cia ntawm cov tshuaj kom tsis txhob muaj lub teeb, av noo, thiab kub.

Siv

Kev Kho Mob Field
5-Aza-2'-deoxy Cytidine yog siv los kho cov kab mob hematological malignancies xws li myelodysplastic syndrome thiab mob myeloid leukemia, thiab kuj tau kawm thiab siv hauv kev kho cov qog nqaij hlav. Decitabine tuaj yeem siv los ntawm kev txhaj tshuaj intravenous, txhaj tshuaj subcutaneous, thiab lwm yam. Nws tuaj yeem coj los ntawm cov hlwb hauv lub cev thiab hloov mus rau hauv daim ntawv active triphosphate, uas tau muab tso rau hauv DNA kom ua haujlwm tau zoo.

Kev tshawb fawb teb
5-} -2}} '}'} 'Tus Cuab Yeej Siv Ua Ntej Ntawm Kev Ua Haujlwm ntawm Daj, Kev Loj Hlob Ntawm Kev Loj Hlob, Kev Loj Hlob thiab Kab Mob Loj Cov.

Tuam txhab tau

Gnechem, nyob hauv Henan xeev, Suav teb, yog ib feem ntawm cov pab pawg Gnee, nrog 22 xyoo kev ua haujlwm zoo rau cov neeg siv khoom lag luam thoob ntiaj teb. Peb muab cov khoom siv raw tshuaj muaj kuab lom thiab tshuaj lom neeg tshwj xeeb rau ntau yam kev muaj peev xwm hauv tsev thiab txawv teb chaws, ua rau peb ib tus neeg ntseeg siab.

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